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    ENTRY       EC 6.3.4.4
    NAME        Adenylosuccinate synthase
                IMP--aspartate ligase
    CLASS       Ligases
                Forming carbon-nitrogen bonds
                Other carbon--nitrogen ligases
    SYSNAME     IMP:L-aspartate ligase (GDP-forming)
    REACTION    GTP + IMP + L-Aspartate = GDP + Orthophosphate +
                N6-(1,2-Dicarboxyethyl)-AMP
    SUBSTRATE   GTP
                IMP
                L-Aspartate
    PRODUCT     GDP
                Orthophosphate
                N6-(1,2-Dicarboxyethyl)-AMP
    PATHWAY     PATH: MAP00230  Purine metabolism
                PATH: MAP00252  Alanine and Aspartate metabolism
    DISEASE     MIM: 103060  Adenylosuccinate synthetase (Ade(-)H-complementing)
    MOTIF       PS: PS00513  G-I-[GR]-P-x-Y-x(2)-K-x(2)-R
    GENES       ECO: ECOLI_4060(purA)
                HIN: HI1633(purA)
                BSU: purA
                MJA: MJ0561
                SYN: sll1823(purA)
                SCE: YNL220W(ADE12)
                HSA: 119656(ADSS)
    DBLINKS     University of Geneva ENZYME DATA BANK: 6.3.4.4
                WIT (What Is There) Metabolic Reconstruction: 6.3.4.4
                PDB: 1ADE    1ADI    1GIN    1HON    1HOO    1HOP
                PIR: A53162  A64370  AJDODS  AJECDS  AJMSDS  S48515  A45027
                     S56402
    ///