********************************************************************************
MAST - Motif Alignment and Search Tool
********************************************************************************
	MAST version 3.0 (Release date: 2004/08/18 09:07:01)

	For further information on how to interpret these results or to get
	a copy of the MAST software please access http://meme.sdsc.edu.
********************************************************************************


********************************************************************************
REFERENCE
********************************************************************************
	If you use this program in your research, please cite:

	Timothy L. Bailey and Michael Gribskov,
	"Combining evidence using p-values: application to sequence homology
	searches", Bioinformatics, 14(48-54), 1998.
********************************************************************************


********************************************************************************
DATABASE AND MOTIFS
********************************************************************************
	DATABASE adh.s (peptide)
	Last updated on Mon Aug 16 21:19:59 2004
	Database contains 33 sequences, 9996 residues

	MOTIFS meme.adh.oops.txt (peptide)
	MOTIF WIDTH BEST POSSIBLE MATCH
	----- ----- -------------------
	  1    29   YSASKFAVRMLTRSMAHEYAPHGIRVNCI
	  2    29   KVVLITGCSSGIGKATAKHLHKEGAKVVL

	PAIRWISE MOTIF CORRELATIONS:
	MOTIF     1
	----- -----
	   2   0.30
	No overly similar pairs (correlation > 0.60) found.

	Random model letter frequencies (from non-redundant database):
	A 0.073 C 0.018 D 0.052 E 0.062 F 0.040 G 0.069 H 0.022 I 0.056 K 0.058 
	L 0.092 M 0.023 N 0.046 P 0.051 Q 0.041 R 0.052 S 0.074 T 0.059 V 0.064 
	W 0.013 Y 0.033 
********************************************************************************


********************************************************************************
SECTION I: HIGH-SCORING SEQUENCES
********************************************************************************
	- Each of the following 33 sequences has E-value less than 10.
	- The E-value of a sequence is the expected number of sequences
	  in a random database of the same size that would match the motifs as
	  well as the sequence does and is equal to the combined p-value of the
	  sequence times the number of sequences in the database.
	- The combined p-value of a sequence measures the strength of the
	  match of the sequence to all the motifs and is calculated by
	    o finding the score of the single best match of each motif
	      to the sequence (best matches may overlap),
	    o calculating the sequence p-value of each score,
	    o forming the product of the p-values,
	    o taking the p-value of the product.
	- The sequence p-value of a score is defined as the
	  probability of a random sequence of the same length containing
	  some match with as good or better a score.
	- The score for the match of a position in a sequence to a motif
	  is computed by by summing the appropriate entry from each column of
	  the position-dependent scoring matrix that represents the motif.
	- Sequences shorter than one or more of the motifs are skipped.
	- The table is sorted by increasing E-value.
********************************************************************************

SEQUENCE NAME                      DESCRIPTION                   E-VALUE  LENGTH
-------------                      -----------                   -------- ------
BUDC_KLETE                         ACETOIN(DIACETYL) REDUCTA...    2.6e-33    241
YRTP_BACSU                         HYPOTHETICAL 25.3 KD PROT...    4.3e-33    238
AP27_MOUSE                         ADIPOCYTE P27 PROTEIN (AP...    4.5e-33    244
HDE_CANTR                          HYDRATASE-DEHYDROGENASE-E...    1.6e-32    906
HDHA_ECOLI                         7-ALPHA-HYDROXYSTEROID DE...    4.9e-31    255
DHII_HUMAN                         CORTICOSTEROID 11-BETA-DE...    8.2e-31    292
FIXR_BRAJA                         FIXR PROTEIN                   2.6e-30    278
DHGB_BACME                         GLUCOSE 1-DEHYDROGENASE B...    3.2e-30    262
NODG_RHIME                         NODULATION PROTEIN G (HOS...    3.4e-29    245
RIDH_KLEAE                         RIBITOL 2-DEHYDROGENASE (...    6.2e-29    249
YINL_LISMO                         HYPOTHETICAL 26.8 KD PROT...    6.6e-29    248
DHMA_FLAS1                         N-ACYLMANNOSAMINE 1-DEHYD...    1.2e-28    270
HMTR_LEIMA                         no comment                     5.1e-28    287
2BHD_STREX                         20-BETA-HYDROXYSTEROID DE...    5.9e-28    255
ENTA_ECOLI                         2,3-DIHYDRO-2,3-DIHYDROXY...    4.8e-27    248
DHB2_HUMAN                         no comment                     1.7e-26    387
BDH_HUMAN                          D-BETA-HYDROXYBUTYRATE DE...    2.8e-26    343
BA72_EUBSP                         7-ALPHA-HYDROXYSTEROID DE...    4.2e-26    249
FVT1_HUMAN                         no comment                     8.9e-26    332
GUTD_ECOLI                         SORBITOL-6-PHOSPHATE 2-DE...    5.1e-25    259
DHB3_HUMAN                         no comment                     8.3e-25    310
3BHD_COMTE                         3-BETA-HYDROXYSTEROID DEH...    1.4e-24    253
LIGD_PSEPA                         C ALPHA-DEHYDROGENASE (EC...    8.1e-24    305
DHES_HUMAN                         ESTRADIOL 17 BETA-DEHYDRO...    2.4e-22    327
RFBB_NEIGO                         no comment                     3.2e-19    346
BPHB_PSEPS                         BIPHENYL-CIS-DIOL DEHYDRO...      1e-18    275
YURA_MYXXA                         no comment                     1.9e-18    258
PCR_PEA                            no comment                     7.2e-18    399
DHCA_HUMAN                         no comment                     1.1e-17    276
ADH_DROME                          ALCOHOL DEHYDROGENASE (EC...    2.7e-14    255
MAS1_AGRRA                         no comment                       3e-14    476
FABI_ECOLI                         no comment                     9.7e-14    262
CSGA_MYXXA                         no comment                     2.5e-12    166

********************************************************************************



********************************************************************************
SECTION II: MOTIF DIAGRAMS
********************************************************************************
	- The ordering and spacing of all non-overlapping motif occurrences
	  are shown for each high-scoring sequence listed in Section I.
	- A motif occurrence is defined as a position in the sequence whose
	  match to the motif has POSITION p-value less than 0.0001.
	- The POSITION p-value of a match is the probability of
	  a single random subsequence of the length of the motif
	  scoring at least as well as the observed match.
	- For each sequence, all motif occurrences are shown unless there
	  are overlaps.  In that case, a motif occurrence is shown only if its
	  p-value is less than the product of the p-values of the other
	  (lower-numbered) motif occurrences that it overlaps.
	- The table also shows the E-value of each sequence.
	- Spacers and motif occurences are indicated by
	   o -d-    `d' residues separate the end of the preceding motif 
		    occurrence and the start of the following motif occurrence
	   o [n]  occurrence of motif `n' with p-value less than 0.0001.
********************************************************************************

SEQUENCE NAME                      E-VALUE   MOTIF DIAGRAM
-------------                      --------  -------------
BUDC_KLETE                          2.6e-33  2_[2]_120_[1]_61
YRTP_BACSU                          4.3e-33  6_[2]_119_[1]_55
AP27_MOUSE                          4.5e-33  7_[2]_112_[1]_67
HDE_CANTR                           1.6e-32  8_[2]_125_[1]_131_[2]_115_[1]_411
HDHA_ECOLI                          4.9e-31  11_[2]_74_[1]_15_[1]_68
DHII_HUMAN                          8.2e-31  34_[2]_119_[1]_81
FIXR_BRAJA                          2.6e-30  36_[2]_123_[1]_61
DHGB_BACME                          3.2e-30  7_[2]_123_[1]_74
NODG_RHIME                          3.4e-29  6_[2]_116_[1]_65
RIDH_KLEAE                          6.2e-29  14_[2]_116_[1]_61
YINL_LISMO                          6.6e-29  5_[2]_75_[2]_15_[1]_66
DHMA_FLAS1                          1.2e-28  14_[2]_121_[1]_77
HMTR_LEIMA                          5.1e-28  6_[2]_157_[1]_66
2BHD_STREX                          5.9e-28  6_[2]_116_[1]_75
ENTA_ECOLI                          4.8e-27  5_[2]_109_[1]_76
DHB2_HUMAN                          1.7e-26  82_[2]_120_[1]_127
BDH_HUMAN                           2.8e-26  55_[2]_123_[1]_107
BA72_EUBSP                          4.2e-26  6_[2]_121_[1]_64
FVT1_HUMAN                          8.9e-26  32_[2]_124_[1]_118
GUTD_ECOLI                          5.1e-25  2_[2]_122_[1]_77
DHB3_HUMAN                          8.3e-25  48_[2]_120_[1]_84
3BHD_COMTE                          1.4e-24  6_[2]_115_[1]_74
LIGD_PSEPA                          8.1e-24  6_[2]_121_[1]_120
DHES_HUMAN                          2.4e-22  2_[2]_50_[2]_44_[1]_144
RFBB_NEIGO                          3.2e-19  6_[2]_129_[1]_153
BPHB_PSEPS                            1e-18  5_[2]_118_[1]_94
YURA_MYXXA                          1.9e-18  65_[2]_22_[2]_14_[1]_70
PCR_PEA                             7.2e-18  25_[1]_32_[2]_284
DHCA_HUMAN                          1.1e-17  4_[2]_159_[1]_55
ADH_DROME                           2.7e-14  6_[2]_116_[1]_75
MAS1_AGRRA                            3e-14  245_[2]_74_[1]_14_[1]_56
FABI_ECOLI                          9.7e-14  6_[2]_123_[1]_75
CSGA_MYXXA                          2.5e-12  51_[2]_7_[1]_50

********************************************************************************



********************************************************************************
SECTION III: ANNOTATED SEQUENCES
********************************************************************************
	- The positions and p-values of the non-overlapping motif occurrences
	  are shown above the actual sequence for each of the high-scoring
	  sequences from Section I.
	- A motif occurrence is defined as a position in the sequence whose
	  match to the motif has POSITION p-value less than 0.0001 as 
	  defined in Section II.
	- For each sequence, the first line specifies the name of the sequence.
	- The second (and possibly more) lines give a description of the 
	  sequence.
	- Following the description line(s) is a line giving the length, 
	  combined p-value, and E-value of the sequence as defined in Section I.
	- The next line reproduces the motif diagram from Section II.
	- The entire sequence is printed on the following lines.
	- Motif occurrences are indicated directly above their positions in the
	  sequence on lines showing
	   o the motif number of the occurrence,
	   o the position p-value of the occurrence,
	   o the best possible match to the motif, and
	   o columns whose match to the motif has a positive score (indicated 
	     by a plus sign).
********************************************************************************


BUDC_KLETE
  ACETOIN(DIACETYL) REDUCTASE (EC 1.1.1.5) (ACETOIN DEHYDROGENASE)
  LENGTH = 241  COMBINED P-VALUE = 7.82e-35  E-VALUE =  2.6e-33
  DIAGRAM: 2_[2]_120_[1]_61

       [2]
       7.9e-21
       KVVLITGCSSGIGKATAKHLHKEGAKVVL
       +++++++++++++++++++++++++ + +
1    MQKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATATAVAAEINQAGGRAVAIKVDVSRRDQVFAAVEQARK

      [1]
      2.6e-21
      YSASKFAVRMLTRSMAHEYAPHGIRVNCI
      +++++++++++++++++++++ ++++++
151  VYSSSKFAVRGLTQTAARDLAPLGITVNGFCPGIVKTPMWAEIDRQCRKRRANRWATARLNLPNASPLAACRSLK


YRTP_BACSU
  HYPOTHETICAL 25.3 KD PROTEIN IN RTP 5'REGION (ORF238)
  LENGTH = 238  COMBINED P-VALUE = 1.31e-34  E-VALUE =  4.3e-33
  DIAGRAM: 6_[2]_119_[1]_55

           [2]
           2.8e-19
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           ++++++++++++++++++++++++ ++ +
1    MQSLQHKTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVEKVAEEVKALGVKAAFAAADVKDADQVNQAVA

         [1]
         1.3e-22
         YSASKFAVRMLTRSMAHEYAPHGIRVNCI
         ++++++++ ++++++++++++++++++++
151  VTSAYSASKFAVLGLTESLMQEVRKHNIRVSALTPSTVASDMSIELNLTDGNPEKVMQPEDLAEYMVAQLKLDPR


AP27_MOUSE
  ADIPOCYTE P27 PROTEIN (AP27)
  LENGTH = 244  COMBINED P-VALUE = 1.37e-34  E-VALUE =  4.5e-33
  DIAGRAM: 7_[2]_112_[1]_67

            [2]
            7.4e-20
            KVVLITGCSSGIGKATAKHLHKEGAKVVL
             +++++++++++++ ++++++++++++++
1    MKLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDWDATEKALGGIG

                                                                              [1
                                                                              4.
                                                                              YS
                                                                              ++
76   PVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYS

     ]
     8e-22
     ASKFAVRMLTRSMAHEYAPHGIRVNCI
     ++++++++++++++++++++ ++++++
151  STKGAMTMLTKAMAMELGPHKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSD


HDE_CANTR
  HYDRATASE-DEHYDROGENASE-EPIMERASE (HDE)
  LENGTH = 906  COMBINED P-VALUE = 4.94e-34  E-VALUE =  1.6e-32
  DIAGRAM: 8_[2]_125_[1]_131_[2]_115_[1]_411

             [2]
             2.5e-19
             KVVLITGCSSGIGKATAKHLHKEGAKVVL
             ++++++++++++++ + +++++ ++++++
1    MSPVDFKDKVVIITGAGGGLGKYYSLEFAKLGAKVVVNDLGGALNGQGGNSKAADVVVDEIVKNGGVAVADYNNV

                 [1]
                 2.8e-13
                 YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                 + +++ ++ ++ ++++++ ++++++ +++
151  PAGLYGNFGQANYASAKSALLGFAETLAKEGAKYNIKANAIAPLARSRMTESILPPPMLEKLGPEKVAPLVLYLS

                           [2]
                           1.5e-24
                           KVVLITGCSSGIGKATAKHLHKEGAKVVL
                           +++++++++ +++++++++++++++++++
301  TNEARKLPANDASGAPTVSLKDKVVLITGAGAGLGKEYAKWFAKYGAKVVVNDFKDATKTVDEIKAAGGEAWPDQ

                     [1]
                     5.2e-18
                     YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                     ++++++++ +++++++ + ++ +++++++
451  NITSTSGIYGNFGQANYSSSKAGILGLSKTMAIEGAKNNIKVNIVAPHAETAMTLTIFREQDKNLYHADQVAPLL


HDHA_ECOLI
  7-ALPHA-HYDROXYSTEROID DEHYDROGENASE (EC 1.1.1.159) (HSDH)
  LENGTH = 255  COMBINED P-VALUE = 1.49e-32  E-VALUE =  4.9e-31
  DIAGRAM: 11_[2]_74_[1]_15_[1]_68

                [2]
                4.3e-21
                KVVLITGCSSGIGKATAKHLHKEGAKVVL
                +++++++++ +++++++++++++++++++
1    MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQEL

                                            [1]
                                            2.9e-05
                                            YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                                            +    ++  ++++  + ++++ +  +
76   SALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAE

             [1]
             8.6e-19
             YSASKFAVRMLTRSMAHEYAPHGIRVNCI
             + +++++ +++++ +++++++++++++++
151  NKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIA


DHII_HUMAN
  CORTICOSTEROID 11-BETA-DEHYDROGENASE (EC 1.1.1.146) (11-DH) (11-BETA- 
  HYDROXYSTEROID DEHYDROGENASE) (11-BETA-HSD)
  LENGTH = 292  COMBINED P-VALUE = 2.49e-32  E-VALUE =  8.2e-31
  DIAGRAM: 34_[2]_119_[1]_81

                                       [2]
                                       3.9e-24
                                       KVVLITGCSSGIGKATAKHLHKEGAKVVL
                                       +++++++++++++++++++++++++++++
1    MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVV

                                     [1]
                                     1.2e-15
                                     YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                                     +++++++++++ ++ +++++ +++++++
151  TVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMK


FIXR_BRAJA
  FIXR PROTEIN
  LENGTH = 278  COMBINED P-VALUE = 7.83e-32  E-VALUE =  2.6e-30
  DIAGRAM: 36_[2]_123_[1]_61

                                         [2]
                                         3.2e-18
                                         KVVLITGCSSGIGKATAKHLHKEGAKVVL
                                         ++++ +++++++++++++ + ++++++
1    MGLDLPNDNLIRGPLPEAHLDRLVDAVNARVDRGEPKVMLLTGASRGIGHATAKLFSEAGWRIISCARQPFDGER

                                           [1]
                                           5.1e-21
                                           YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                                           +  +++++ ++++++++++++++++++++
151  APILLAQGLFDELRAASGSIVNVTSIAGSRVHPFAGSAYATSKAALASLTRELAHDYAPHGIRVNAIAPGEIRTD


DHGB_BACME
  GLUCOSE 1-DEHYDROGENASE B (EC 1.1.1.47)
  LENGTH = 262  COMBINED P-VALUE = 9.77e-32  E-VALUE =  3.2e-30
  DIAGRAM: 7_[2]_123_[1]_74

            [2]
            4.4e-19
            KVVLITGCSSGIGKATAKHLHKEGAKVVL
            +++++++ + +++++++++++++ +++++
1    MYKDLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEEIKKVGGEAIAVKGDVTVESDVIN

              [1]
              5.3e-20
              YSASKFAVRMLTRSMAHEYAPHGIRVNCI
              + +++++++ +++++++++++++++++++
151  KIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNIGPGAINTPINAEKFADPEQRADVESMIPMGYIGEPEE


NODG_RHIME
  NODULATION PROTEIN G (HOST-SPECIFICITY OF NODULATION PROTEIN C)
  LENGTH = 245  COMBINED P-VALUE = 1.03e-30  E-VALUE =  3.4e-29
  DIAGRAM: 6_[2]_116_[1]_65

           [2]
           4.0e-16
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
            +++++++++ ++ ++++ ++++++ + +
1    MFELTGRKALVTGASGAIGGAIARVLHAQGAIVGLHGTQIEKLETLATELGDRVKLFPANLANRDEVKALGQRAE

      [1]
      7.3e-22
      YSASKFAVRMLTRSMAHEYAPHGIRVNCI
      +++++++++++++++++++++ +++++++
151  NYCASKAGMIGFSKSLAQEIATRNITVNCVAPGFIESAMTDKLNHKQKEKIMVAIPIHRMGTGTEVASAVAYLAS


RIDH_KLEAE
  RIBITOL 2-DEHYDROGENASE (EC 1.1.1.56) (RDH)
  LENGTH = 249  COMBINED P-VALUE = 1.88e-30  E-VALUE =  6.2e-29
  DIAGRAM: 14_[2]_116_[1]_61

                   [2]
                   7.0e-21
                   KVVLITGCSSGIGKATAKHLHKEGAKVVL
                   +++ +++++++++++++++++ +++++++
1    MKHSVSSMNTSLSGKVAAITGAASGIGLECARTLLGAGAKVVLIDREGEKLNKLVAELGENAFALQVDLMQADQV

              [1]
              7.4e-17
              YSASKFAVRMLTRSMAHEYAPHGIRVNCI
              ++++++++++++++ +++++++++++ ++
151  VVPVIWEPVYTASKFAVQAFVHTTRRQVAQYGVRVGAVLPGPVVTALLDDWPKAKMDEALANGSLMQPIEVAESV


YINL_LISMO
  HYPOTHETICAL 26.8 KD PROTEIN IN INLA 5'REGION (ORFA)
  LENGTH = 248  COMBINED P-VALUE = 1.99e-30  E-VALUE =  6.6e-29
  DIAGRAM: 5_[2]_75_[2]_15_[1]_66

          [2]
          2.9e-23
          KVVLITGCSSGIGKATAKHLHKEGAKVVL
          ++++++++++++++++++ +++++++ ++
1    MTIKNKVIIITGASSGIGKATALLLAEKGAKLVLAARRVEKLEKIVQIIKANSGEAIFAKTDVTKREDNKKLVEL

                                       [2]
                                       3.8e-05
                                       KVVLITGCSSGIGKATAKHLHKEGAKVVL
                                         + + +   ++   +    +++  ++ +
76   AIERYGKVDAIFLNAGIMPNSPLSALKEDEWEQMIDINIKGVLNGIAAVLPSFIAQKSGHIIATSSVAGLKAYPG

        [1]
        1.9e-14
        YSASKFAVRMLTRSMAHEYAPHGIRVNCI
        +++++++++ +++ ++++ ++++ ++++
151  GAVYGATKWAVRDLMEVLRMESAQEGTNIRTATIYPAAINTELLETITDKETEQGMTSLYKQYGITPDRIASIVA


DHMA_FLAS1
  N-ACYLMANNOSAMINE 1-DEHYDROGENASE (EC 1.1.1.233) (NAM-DH) 
  LENGTH = 270  COMBINED P-VALUE = 3.65e-30  E-VALUE =  1.2e-28
  DIAGRAM: 14_[2]_121_[1]_77

                   [2]
                   2.0e-19
                   KVVLITGCSSGIGKATAKHLHKEGAKVVL
                   + +++++++++++++++++ +++++++++
1    TTAGVSRRPGRLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPGAIPIACDLADRAAIDA

                   [1]
                   4.2e-18
                   YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                   + ++++++ +++++++++++++++ ++++
151  GSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLARHGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRP


HMTR_LEIMA
  no comment
  LENGTH = 287  COMBINED P-VALUE = 1.55e-29  E-VALUE =  5.1e-28
  DIAGRAM: 6_[2]_157_[1]_66

           [2]
           1.6e-17
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           ++++++++++ +++++++ ++++++ +++
1    MTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVS

                                               [1]
                                               2.1e-19
                                               YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                                               +++++++++++++++++++++ +++++++
151  PYFLIKAFAHRSRHPSQASRTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL


2BHD_STREX
  20-BETA-HYDROXYSTEROID DEHYDROGENASE (EC 1.1.1.53)
  LENGTH = 255  COMBINED P-VALUE = 1.78e-29  E-VALUE =  5.9e-28
  DIAGRAM: 6_[2]_116_[1]_75

           [2]
           7.1e-18
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           +++++++++++++ + +++ +++++++++
1    MNDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAR

      [1]
      6.8e-19
      YSASKFAVRMLTRSMAHEYAPHGIRVNCI
      +++++++++++++ +++++++ +++++++
151  SYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVGNEPGEIAGAVVKLL


ENTA_ECOLI
  2,3-DIHYDRO-2,3-DIHYDROXYBENZOATE DEHYDROGENASE (EC 1.3.1.28)
  LENGTH = 248  COMBINED P-VALUE = 1.45e-28  E-VALUE =  4.8e-27
  DIAGRAM: 5_[2]_109_[1]_76

          [2]
          3.7e-20
          KVVLITGCSSGIGKATAKHLHKEGAKVVL
          +++++++++++++++++++++++++++
1    MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDA

                                                                         [1]
                                                                         1.2e-15
                                                                         YSASKFA
                                                                         +++++++
76   LVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAA

     
     
     VRMLTRSMAHEYAPHGIRVNCI
     ++++  +  ++++ ++++++++
151  LKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFL


DHB2_HUMAN
  no comment
  LENGTH = 387  COMBINED P-VALUE = 5.05e-28  E-VALUE =  1.7e-26
  DIAGRAM: 82_[2]_120_[1]_127


            [2]
            3.4e-17
            KVVLITGCSSGIGKATAKHLHKEGAKVVL
            + ++++++++++++++++++ + ++ +++
76   ELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYS

           [1]
           1.7e-18
           YSASKFAVRMLTRSMAHEYAPHGIRVNCI
           +++++++++++++ ++++++++++++ ++
226  MERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYI


BDH_HUMAN
  D-BETA-HYDROXYBUTYRATE DEHYDROGENASE PRECURSOR (EC 1.1.1.30) (BDH) 
  (3-HYDROXYBUTYRATE DEHYDROGENASE) (FRAGMENT)
  LENGTH = 343  COMBINED P-VALUE = 8.57e-28  E-VALUE =  2.8e-26
  DIAGRAM: 55_[2]_123_[1]_107

                                                            [2]
                                                            2.3e-18
                                                            KVVLITGCSSGIGKATAKHL
                                                            + +++++++++ ++++++++
1    GLRPPPPGRFSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFSLAKHL

     
     
     HKEGAKVVL
     +++++ +++
76   HSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVFRSEEVEKVVGDCPFEPEGPEKGMWGLVNNAGISTF

                                                              [1]
                                                              5.5e-17
                                                              YSASKFAVRMLTRSMAHE
                                                              ++ +++++++++++++++
151  GEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE

     
     
     YAPHGIRVNCI
     +++ +++++++
226  MYPLGVKVSVVEPGNFIAATSLYNPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVID


BA72_EUBSP
  7-ALPHA-HYDROXYSTEROID DEHYDROGENASE (EC 1.1.1.159) (BILE ACID 
  7-DEHYDROXYLASE) (BILE ACID-INDUCIBLE PROTEIN)
  LENGTH = 249  COMBINED P-VALUE = 1.28e-27  E-VALUE =  4.2e-26
  DIAGRAM: 6_[2]_121_[1]_64

           [2]
           2.6e-18
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           ++++++++ ++++++ ++ ++ +++++ +
1    MNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFAPDLTSRDAVMAA

           [1]
           1.5e-16
           YSASKFAVRMLTRSMAHEYAPHGIRVNCI
           + +++++++++++ + +++ +++++++++
151  SLSGVGYPASKASVIGLTHGLGREIIRKNIRVVGVAPGVVNTDMTNGNPPEIMEGYLKALPMKRMLEPEEIANVY


FVT1_HUMAN
  no comment
  LENGTH = 332  COMBINED P-VALUE = 2.70e-27  E-VALUE =  8.9e-26
  DIAGRAM: 32_[2]_124_[1]_118

                                     [2]
                                     2.3e-17
                                     KVVLITGCSSGIGKATAKHLHKEGAKVVL
                                      ++++++++++++++++++++++++ + +
1    MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKE

                                        [1]
                                        1.9e-17
                                        YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                                        +++++++++++ ++++++++++++++++
151  YPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFA


GUTD_ECOLI
  SORBITOL-6-PHOSPHATE 2-DEHYDROGENASE (EC 1.1.1.140) (GLUCITOL-6- PHOSPHATE 
  DEHYDROGENASE) (KETOSEPHOSPHATE REDUCTASE)
  LENGTH = 259  COMBINED P-VALUE = 1.54e-26  E-VALUE =  5.1e-25
  DIAGRAM: 2_[2]_122_[1]_77

       [2]
       1.5e-14
       KVVLITGCSSGIGKATAKHLHKEGAKVVL
       +++++ ++++ ++  +++ ++++++++ +
1    MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQEINAEYGESMAYGFGADATSEQSCLALSRGV

        [1]
        3.0e-19
        YSASKFAVRMLTRSMAHEYAPHGIRVNCI
        +++++++ +++++++++++++++++++++
151  NSGYSAAKFGGVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPDQVEQYYIDKVPLKRGC


DHB3_HUMAN
  no comment
  LENGTH = 310  COMBINED P-VALUE = 2.53e-26  E-VALUE =  8.3e-25
  DIAGRAM: 48_[2]_120_[1]_84

                                                     [2]
                                                     7.4e-19
                                                     KVVLITGCSSGIGKATAKHLHKEGAKV
                                                     +++++++++ ++++++  ++++++ ++
1    MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYYKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNV

     
     
     VL
     ++
76   VLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEI

                                                    [1]
                                                    6.7e-15
                                                    YSASKFAVRMLTRSMAHEYAPHGIRVNC
                                                    ++++++++++++++++ +++ + + +++
151  QSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQV

     
     
     I
     +
226  LTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYV


3BHD_COMTE
  3-BETA-HYDROXYSTEROID DEHYDROGENASE (EC 1.1.1.51)
  LENGTH = 253  COMBINED P-VALUE = 4.25e-26  E-VALUE =  1.4e-24
  DIAGRAM: 6_[2]_115_[1]_74

           [2]
           2.6e-18
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           +++++++++++ ++++++ ++ +++++
1    TNRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVSSEADWTLVMAAVQ

     [1]
     5.1e-15
     YSASKFAVRMLTRSMAHEYAPHGIRVNCI
     +++++++++++++++++ +++++  +++
151  YSASKAAVSALTRAAALSCRKQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQL


LIGD_PSEPA
  C ALPHA-DEHYDROGENASE (EC -.-.-.-)
  LENGTH = 305  COMBINED P-VALUE = 2.45e-25  E-VALUE =  8.1e-24
  DIAGRAM: 6_[2]_121_[1]_120

           [2]
           6.5e-17
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           +++ +++++++ ++  ++ + ++++++++
1    MKDFQDQVAFITGGASGAGFGQAKVFGQAGAKIVVADVRAEAVEKAVAELEGLGITAHGIVLDIMDREAYARAAD

           [1]
           7.9e-16
           YSASKFAVRMLTRSMAHEYAPHGIRVNCI
           +++++++ +++++ +++ ++++++ ++++
151  SALAGPYSAAKAASINLMEGYRQGLEKYGIGVSVCTPANIKSNIAEASRLRPAKYGTSGYVENEESIASLHSIHQ


DHES_HUMAN
  ESTRADIOL 17 BETA-DEHYDROGENASE (EC 1.1.1.62) (20 ALPHA-HYDROXYSTEROID 
  DEHYDROGENASE) (E2DH) (17-BETA-HSD) (PLACENTAL 17-BETA-HYDROXYSTEROID 
  DEHYDROGENASE)
  LENGTH = 327  COMBINED P-VALUE = 7.31e-24  E-VALUE =  2.4e-22
  DIAGRAM: 2_[2]_50_[2]_44_[1]_144

       [2]
       1.4e-14
       KVVLITGCSSGIGKATAKHLHKEGAKVVL
       +++++++++++++++++ +++++ ++ +
1    ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAA

           [2]
           9.3e-05
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
            ++ +  ++ ++++   ++ + + +   +
76   RERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLP

         [1]
         1.0e-16
         YSASKFAVRMLTRSMAHEYAPHGIRVNCI
         +++++++++++++++++ + + +++ + +
151  FNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQV


RFBB_NEIGO
  no comment
  LENGTH = 346  COMBINED P-VALUE = 9.68e-21  E-VALUE =  3.2e-19
  DIAGRAM: 6_[2]_129_[1]_153

           [2]
           1.8e-13
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           ++++++++++ ++ +++++ +++    ++
1    MQTEGKKNILVTGGAGFIGSAVVRHIIQNTRDSVVNLDKLTYAGNLESLTDIADNPRYAFEQVDICDRAELDRVF

                   [1]
                   1.0e-14
                   YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                   +++++++ +++++++++ ++   ++ ++
151  DLFTETTPYAPSSPYSASKAAADHLVRAWQRTYRLPSIVSNCSNNYGPRQFPEKLIPLMILNALSGKPLPVYGDG


BPHB_PSEPS
  BIPHENYL-CIS-DIOL DEHYDROGENASE (EC 1.3.1.-)
  LENGTH = 275  COMBINED P-VALUE = 3.02e-20  E-VALUE =    1e-18
  DIAGRAM: 5_[2]_118_[1]_94

          [2]
          8.6e-15
          KVVLITGCSSGIGKATAKHLHKEGAKVVL
            +++++++++++++++ +++++    ++
1    MKLKGEAVLITGGASGLGRALVDRFVAEAKVAVLDKSAERLAELETDLGDNVLGIVGDVRSLEDQKQAASRCVAR

       [1]
       1.2e-12
       YSASKFAVRMLTRSMAHEYAPHGIRVNCI
       ++++++++++++++++++++++  +  +
151  PLYTAAKQAIVGLVRELAFELAPYVRVNGVGPGGMNSDMRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEE


YURA_MYXXA
  no comment
  LENGTH = 258  COMBINED P-VALUE = 5.64e-20  E-VALUE =  1.9e-18
  DIAGRAM: 65_[2]_22_[2]_14_[1]_70

                                                                      [2]
                                                                      5.6e-05
                                                                      KVVLITGCSS
                                                                        + ++ ++
1    RQHTGGLHGGDELPDGVGDGCLQRPGTRAGAVARQAGVRVFAAGRRLPQLQAADEAPGGRRHRGARGVDVTKADA

                                              [2]
                                              5.7e-08
     GIGKATAKHLHKEGAKVVL                      KVVLITGCSSGIGKATAKHLHKEGAKVVL
      + +  +++  + +   ++                        + +++++  +   + ++  ++  + +
76   TLERIRALDAEAGGLDLVVANAGVGGTTNAKRLPWERVRGIIDTNVTGAAATLSAVLPQMVERKRGHLVGVSSLA

              [1]
              3.8e-19
              YSASKFAVRMLTRSMAHEYAPHGIRVNCI
              +++++++++ ++++++++++ ++++++++
151  GFRGLPATRYSASKAFLSTFMESLRVDLRGTGVRVTCIYPGFVKSELTATNNFPMPFLMETHDAVELMGKGIVRG


PCR_PEA
  no comment
  LENGTH = 399  COMBINED P-VALUE = 2.17e-19  E-VALUE =  7.2e-18
  DIAGRAM: 25_[1]_32_[2]_284

                              [1]
                              1.7e-08
                              YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                                ++ ++++++++++  +   +  +++ +
1    MALQTASMLPASFSIPKEGKIGASLKDSTLFGVSSLSDSLKGDFTSSALRCKELRQKVGAVRAETAAPATPAVNK

                [2]
                1.9e-18
                KVVLITGCSSGIGKATAKHLHKEGAKVVL
                 +++++++++++++++++++++++ + ++
76   SSSEGKKTLRKGNVVITGASSGLGLATAKALAESGKWHVIMACRDYLKAARAAKSAGLAKENYTIMHLDLASLDS


DHCA_HUMAN
  no comment
  LENGTH = 276  COMBINED P-VALUE = 3.43e-19  E-VALUE =  1.1e-17
  DIAGRAM: 4_[2]_159_[1]_55

         [2]
         4.0e-16
         KVVLITGCSSGIGKATAKHLHKEGAKVVL
         ++++++++++++++++++++++  +  ++
1    SSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDF

                                               [1]
                                               2.9e-10
                                               YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                                               ++ ++ +++ +++ +++ +++++   +++
151  PELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNAC


ADH_DROME
  ALCOHOL DEHYDROGENASE (EC 1.1.1.1)
  LENGTH = 255  COMBINED P-VALUE = 8.17e-16  E-VALUE =  2.7e-14
  DIAGRAM: 6_[2]_116_[1]_75

           [2]
           1.1e-10
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           ++++   + +++++ + ++++++  +  +
1    SFTLTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPYDVTVPIAETTKL

      [1]
      3.6e-12
      YSASKFAVRMLTRSMAHEYAPHGIRVNCI
      ++ ++++++++++++++    ++++ +++
151  VYSGTKAAVVNFTSSLAKLAPITGVTAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLAHPTQPSLACAENFVKA


MAS1_AGRRA
  no comment
  LENGTH = 476  COMBINED P-VALUE = 9.22e-16  E-VALUE =    3e-14
  DIAGRAM: 245_[2]_74_[1]_14_[1]_56


                         [2]
                         2.9e-15
                         KVVLITGCSSGIGKATAKHLHKEGAKVVL
                         +++++ + +++ ++++++++++++++  +
226  GRVLHFRRGFSHWTVEIHQSPVILVSGSNRGVGKAIAEDLIAHGYRLSLGARKVKDLEVAFGPQDEWLHYARFDA

                                                     [1]
                                                     4.0e-08
                                                     YSASKFAVRMLTRSMAHEYAPHGIRVN
                                                     +  + + +++   ++ + +++   +++
301  EDHGTMAAWVTAAVEKFGRIDGLVNNAGYGEPVNLDKHVDYQRFHLQWYINCVAPLRMTELCLPHLYETGSGRIV

                     [1]
                     8.7e-05
     CI              YSASKFAVRMLTRSMAHEYAPHGIRVNCI
     ++              + +++ ++ +++++ ++     +     +
376  NINSMSGQRVLNPLVGYNMTKHALGGLTKTTQHVGWDRRCAAIDICLGFVATDMSAWTDLIASKDMIQPEDIAKL


FABI_ECOLI
  no comment
  LENGTH = 262  COMBINED P-VALUE = 2.94e-15  E-VALUE =  9.7e-14
  DIAGRAM: 6_[2]_123_[1]_75

           [2]
           4.5e-10
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           +++++++ ++ +  ++ ++ +++     +
1    MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMF

             [1]
             3.1e-12
             YSASKFAVRMLTRSMAHEYAPHGIRVNCI
             ++ +++++++ +++++  +++++++++++
151  RAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDV


CSGA_MYXXA
  no comment
  LENGTH = 166  COMBINED P-VALUE = 7.50e-14  E-VALUE =  2.5e-12
  DIAGRAM: 51_[2]_7_[1]_50

                                                        [2]
                                                        9.0e-08
                                                        KVVLITGCSSGIGKATAKHLHKEG
                                                        + ++  +  ++  + +++   +++
1    MRAFATNVCTGPVDVLINNAGVSGLWCALGDVDYADMARTFTINALGPLRVTSAMLPGLRQGALRRVAHVTSRMG

                 [1]
                 1.3e-12
     AKVVL       YSASKFAVRMLTRSMAHEYAPHGIRVNCI
     +           + ++++++ + ++++  ++++++ + + +
76   SLAANTDGGAYAYRMSKAALNMAVRSMSTDLRPEGFVTVLLHPGWVQTDMGGPDATLPAPDSVRGMLRVIDGLNP

********************************************************************************


CPU: pmgm2
Time 0.250000 secs.

mast meme.adh.oops.txt -text -stdout
